1. Long-term Smoking, Alcohol Consumption, and Betel Nut Chewing
Most oral cancer patients have a long history of smoking and drinking. Studies show that individuals who smoke and drink have a 15.5 times higher risk of developing oral cancer compared to those who do neither. In recent years, the incidence of oral cancer among betel nut chewers has also risen significantly. Betel nut is classified as a Group 1 carcinogen by the World Health Organization (WHO). Frequent chewing of betel nut significantly increases the risk of oral mucosal lesions, which in turn raises the likelihood of developing oral cancer.
2. HPV Infection
The human papillomavirus (HPV), which is transmitted through sexual activity and close contact, is another major risk factor. While HPV is known for causing cervical cancer in women, it has also been increasingly linked to the rise in oral cancer cases in recent years. Research shows that around 70% of newly diagnosed oral cancer patients are infected with HPV, making it an even more prominent carcinogenic factor than tobacco.
3. Poor Oral Hygiene Habits
Poor oral hygiene allows bacteria and fungi to grow and multiply in the mouth, facilitating the formation of nitrosamines, a known Group 1 carcinogen. Chronic inflammation from poor dental care can lead to cell overgrowth, making the tissue more vulnerable to carcinogens and promoting the development of oral cancer.
4. Chronic Irritation and Injury
Habits such as eating excessively hot or spicy food, or having sharp tooth edges, root fragments, or ill-fitting dentures, can lead to long-term irritation of the oral mucosa. This chronic irritation may result in persistent ulcers, which can eventually turn cancerous.
5. Malnutrition
Deficiencies in vitamin A, vitamin C, iron, selenium, and zinc are associated with a higher risk of oral cancer. Inadequate intake of total protein and animal protein may also be contributing factors.
If you have any questions about oral cancer, feel free to reach out.
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