{"id":20789,"date":"2024-12-10T10:50:05","date_gmt":"2024-12-10T02:50:05","guid":{"rendered":"https:\/\/www.hkioc.com.hk\/?p=20789"},"modified":"2024-12-11T10:50:38","modified_gmt":"2024-12-11T02:50:38","slug":"car-t","status":"publish","type":"post","link":"https:\/\/www.hkioc.com.hk\/zh-hans\/car-t\/","title":{"rendered":"\u7f8e\u56fdCAR-T\u65b0\u7597\u6cd5ALLO-316\u6cbb\u7597\u80be\u764c\u6f5c\u529b\u5de8\u5927"},"content":{"rendered":"\n

\u6458\u8981<\/strong><\/strong><\/p>\n\n\n\n

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RMAT\u8d44\u683c\u4e3b\u8981\u7528\u4e8e\u90a3\u4e9b\u4ee5\u518d\u751f\u6216\u4fee\u590d\u4eba\u4f53\u7ec4\u7ec7\u3001\u5668\u5b98\u548c\u7ec6\u80de\u4e3a\u76ee\u6807\u7684\u7597\u6cd5\uff0c\u5305\u62ec\u7ec6\u80de\u7597\u6cd5\u3001\u57fa\u56e0\u7597\u6cd5\u3001\u7ec4\u7ec7\u5de5\u7a0b\u7b49\uff0c\u5c24\u5176\u662f\u7528\u4e8e\u6cbb\u7597\u4e25\u91cd\u6216\u5371\u53ca\u751f\u547d\u7684\u75be\u75c5\u3002RMAT\u8d44\u683c\u7684\u6cbb\u7597\u65b9\u6cd5\u53ef\u4ee5\u83b7\u5f97FDA\u7684\u5feb\u901f\u901a\u9053\u548c\u4f18\u5148\u5ba1\u8bc4\u8d44\u683c\uff0c\u52a0\u901f\u7814\u53d1\u8fc7\u7a0b\uff0c\u5e2e\u52a9\u60a3\u8005\u66f4\u5feb\u83b7\u5f97\u6709\u6548\u6cbb\u7597\u3002<\/p>\n\n\n\n


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  1. \u5728\u6240\u6709\u53ef\u8bc4\u4f30\u7597\u6548\u7684\u60a3\u8005\u4e2d\uff1a<\/li><\/ol>\n\n\n\n

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    2.\u5728CD70\u9633\u6027\u75be\u75c5\u60a3\u8005\u4e2d\uff1a<\/p>\n\n\n\n

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    <\/strong>\u5173\u4e8eALLO-316<\/strong>
    <\/strong><\/p>\n\n\n\n

    ALLO-316\u662f\u5f00\u53d1\u7684\u4e00\u79cd\u540c\u79cd\u5f02\u4f53\u5d4c\u5408\u6297\u539f\u53d7\u4f53T\u7ec6\u80de\u4ea7\u54c1\uff0c\u9776\u5411CD70\u6297\u539f\u3002<\/p>\n\n\n\n

    CD70\u5728\u591a\u79cd\u6076\u6027\u80bf\u7624\u4e2d\u9ad8\u8868\u8fbe\uff0c\u5305\u62ec\u80be\u7ec6\u80de\u764c\uff08RCC\uff09\u548c\u6025\u6027\u9ad3\u6027\u767d\u8840\u75c5\uff08AML\uff09\u3002ALLO-316\u65e8\u5728\u901a\u8fc7\u8bc6\u522b\u5e76\u653b\u51fb\u8868\u8fbeCD70\u7684\u764c\u7ec6\u80de\uff0c\u63d0\u4f9b\u4e00\u79cd\u201c\u73b0\u6210\u7684\u201d\u7ec6\u80de\u6cbb\u7597\u65b9\u6848\u3002<\/p>\n\n\n\n

    2022\u5e743\u6708\uff0c\u7f8e\u56fd\u98df\u54c1\u836f\u54c1\u76d1\u7763\u7ba1\u7406\u5c40\uff08FDA\uff09\u66fe\u6388\u4e88ALLO-316\u5feb\u901f\u901a\u9053\uff08FTD\uff09\u8d44\u683c\u3002<\/p>\n\n\n\n

    \u5feb\u901f\u901a\u9053\uff08FTD\uff09\u662f\u7f8e\u56fd\u98df\u54c1\u836f\u54c1\u76d1\u7763\u7ba1\u7406\u5c40\uff08FDA\uff09\u8bbe\u7acb\u7684\u4e00\u9879\u52a0\u901f\u5ba1\u6279\u7a0b\u5e8f\uff0c\u65e8\u5728\u4fc3\u8fdb\u7528\u4e8e\u6cbb\u7597\u4e25\u91cd\u75be\u75c5\u4e14\u5177\u6709\u672a\u6ee1\u8db3\u533b\u7597\u9700\u6c42\u7684\u65b0\u836f\u548c\u7597\u6cd5\u7684\u5f00\u53d1\uff0c\u4f7f\u5176\u66f4\u5feb\u5730\u8fdb\u5165\u5e02\u573a\u5e76\u60e0\u53ca\u60a3\u8005\u3002<\/p>\n\n\n\n

    \u6388\u4e88\u4f9d\u636e<\/strong>
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    TRAVERSE\u8bd5\u9a8c\u65e8\u5728\u8bc4\u4f30ALLO-316\u5728\u665a\u671f\u6216\u8f6c\u79fb\u6027\u80be\u7ec6\u80de\u764c\uff08RCC\uff09\u60a3\u8005\u4e2d\u7684\u5b89\u5168\u6027\u3001\u8010\u53d7\u6027\u548c\u6297\u80bf\u7624\u6d3b\u6027\u3002<\/p>\n\n\n\n

    \u6570\u636e\u7ed3\u679c<\/strong><\/strong><\/p>\n\n\n\n

    \u6b64\u524d\u62a5\u544a\u7684\u6570\u636e\u663e\u793a\uff1a<\/p>\n\n\n\n

    1.\u5728\u6240\u6709\u53ef\u8bc4\u4f30\u7597\u6548\u7684\u60a3\u8005\u4e2d\uff1a<\/p>\n\n\n\n

    \u5ba2\u89c2\u7f13\u89e3\u7387\uff08ORR\uff09\u4e3a17%\uff0c\u5373\u670917%\u7684\u60a3\u8005\u80bf\u7624\u663e\u8457\u7f29\u5c0f\u6216\u5b8c\u5168\u6d88\u5931\u3002\u75be\u75c5\u63a7\u5236\u7387\uff08DCR\uff09\u4e3a89%\uff0c\u5373\u670989%\u7684\u60a3\u8005\u75be\u75c5\u5f97\u5230\u6709\u6548\u63a7\u5236\u3002<\/p>\n\n\n\n

    2.\u5728CD70\u9633\u6027\u75be\u75c5\u60a3\u8005\u4e2d\uff1a<\/p>\n\n\n\n

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    4.\u6700\u957f\u7f13\u89e3\u6301\u7eed\u65f6\u95f4\u4e3a8\u4e2a\u6708\uff0c\u5e76\u4e14\u5728CD70\u9ad8\u8868\u8fbe\u7684\u60a3\u8005\u4e2d\u89c2\u5bdf\u5230\u80bf\u7624\u7f29\u5c0f\u8d8b\u52bf\u3002<\/p>\n\n\n\n


    \u5b89\u5168\u6027<\/strong>
    <\/p>\n\n\n\n

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