{"id":38882,"date":"2026-03-11T20:07:35","date_gmt":"2026-03-11T12:07:35","guid":{"rendered":"https:\/\/www.hkioc.com.hk\/?p=38882"},"modified":"2026-03-13T13:40:05","modified_gmt":"2026-03-13T05:40:05","slug":"%e9%92%88%e5%af%b9%e5%88%9d%e6%b2%bbnsclc%ef%bc%9a%e3%80%8c%e5%ae%97%e8%89%be%e6%9b%bf%e5%b0%bc%e3%80%8d%e8%8e%b7%e5%be%97fda%e7%89%b9%e6%89%b9","status":"publish","type":"post","link":"https:\/\/www.hkioc.com.hk\/zh-hans\/%e9%92%88%e5%af%b9%e5%88%9d%e6%b2%bbnsclc%ef%bc%9a%e3%80%8c%e5%ae%97%e8%89%be%e6%9b%bf%e5%b0%bc%e3%80%8d%e8%8e%b7%e5%be%97fda%e7%89%b9%e6%89%b9\/","title":{"rendered":"\u9488\u5bf9\u521d\u6cbbNSCLC\uff1a\u300c\u5b97\u827e\u66ff\u5c3c\u300d\u83b7\u5f97FDA\u7279\u6279"},"content":{"rendered":"\n<p><strong>\u2022<\/strong><strong>&nbsp;<\/strong><strong>\u91cc\u7a0b\u7891\u610f\u4e49\uff1a<\/strong>\u5b97\u827e\u66ff\u5c3c\uff08zongertinib\uff09\u662f\u5168\u7403\u9996\u4e2a\u4e14\u76ee\u524d\u552f\u4e00\u83b7\u6279\u7684\u53e3\u670dHER2\u916a\u6c28\u9178\u6fc0\u9176\u6291\u5236\u5242\uff0c\u586b\u8865\u4e86HER2\u7a81\u53d8\u80ba\u764c\u9776\u5411\u6cbb\u7597\u7a7a\u767d\u3002<\/p>\n\n\n\n<p><strong>\u2022<\/strong><strong>&nbsp;<\/strong><strong>\u5ba1\u6279\u8fdb\u9636\uff1a<\/strong>2025\u5e748\u6708\u76f8\u7ee7\u83b7FDA\u548cNMPA\u6279\u51c6\u7528\u4e8e\u5b58\u5728HER2\u916a\u6c28\u9178\u6fc0\u9176\u7ed3\u6784\u57df\u6fc0\u6d3b\u7a81\u53d8\u4e14\u65e2\u5f80\u63a5\u53d7\u8fc7\u7cfb\u7edf\u6027\u6cbb\u7597\u7684\u4e0d\u53ef\u5207\u9664\u6216\u8f6c\u79fb\u6027\u975e\u9cde\u72b6\u975e\u5c0f\u7ec6\u80de\u80ba\u764c\u6210\u4eba\u60a3\u8005\uff1b2026\u5e742\u6708\u518d\u83b7FDA\u52a0\u901f\u6279\u51c6\u7528\u4e8e\u4e00\u7ebf\u6cbb\u7597\uff0c\u5b9e\u73b0\u4ece\u540e\u7ebf\u5230\u4e00\u7ebf\u7684\u5168\u9762\u8986\u76d6\u3002<\/p>\n\n\n\n<p><strong>\u2022<\/strong><strong>&nbsp;<\/strong><strong>\u7597\u6548\u663e\u8457\uff1a<\/strong>\u4e00\u7ebf\u6cbb\u7597\u5ba2\u89c2\u7f13\u89e3\u7387\u9ad8\u8fbe76%\uff0c\u540e\u7ebf\u6cbb\u7597\u8fbe71%\uff0c\u4e14\u5bf9\u8111\u8f6c\u79fb\u60a3\u8005\u663e\u793a\u6d3b\u6027\u3002<\/p>\n\n\n\n<p>\u5b97\u827e\u66ff\u5c3c\u7528\u4e8e\u4e00\u7ebf\u6cbb\u7597HER2\u7a81\u53d8\u975e\u5c0f\u7ec6\u80de\u80ba\u764c\u7684\u9002\u5e94\u75c7\uff0c\u76ee\u524d\u4ecd\u672a\u5728\u5185\u5730\u83b7\u6279\u3002\u5982\u75c5\u4eba\u5e0c\u671b\u4e86\u89e3\u5982\u4f55\u901a\u8fc7\u300c\u6307\u5b9a\u60a3\u8005\u7528\u836f\u8ba1\u5212\u300d\uff08Named Patient Access Program\uff09\u83b7\u53d6\u6b64\u836f\u7269\uff0c\u53ef\u67e5\u8be2\u76f8\u5173\u8be6\u60c5\u3002<\/p>\n\n\n\n<p>* Named Patient Access Program\uff0c\uff08\u7b80\u79f0NPA\uff09\u6307\u5b9a\u836f\u7269\u4f7f\u7528\u8ba1\u5212\uff0c\u4ea6\u79f0\u300c\u65b0\u836f\u7eff\u8272\u901a\u9053\u300d\uff0c\u7b26\u5408\u4ee5\u4e0b\u4e24\u79cd\u60c5\u51b5\u7684\u75c5\u4eba\uff0c\u53ef\u900f\u8fc7\u6b64\u8ba1\u5212\u4f7f\u7528\u76f8\u5173\u7684\u521b\u65b0\u764c\u75c7\u836f\u7269\uff1a<\/p>\n\n\n\n<p>1.\u75c5\u4eba\u6240\u9700\u7684\u521b\u65b0\u836f\u7269\u5728\u9999\u6e2f\u5c1a\u672a\u6ce8\u518c\uff0c\u4f46\u5df2\u5728\u6b27\u7f8e\u6216\u5185\u5730\u83b7\u6279\u4e0a\u5e02\uff1b<br>2.\u5fc5\u987b\u7ecf\u9999\u6e2f\u7684\u533b\u751f\uff08\u4e3b\u8981\u4e3a\u4e34\u5e8a\u80bf\u7624\u79d1\u6216\u5185\u79d1\u80bf\u7624\u79d1\u4e13\u79d1\u533b\u751f\uff09\u8bca\u65ad\u53ca\u8bc4\u4f30\u540e\uff0c\u786e\u8ba4\u75c5\u4eba\u60c5\u51b5\u9002\u5408\u6216\u6709\u9700\u8981\u4f7f\u7528\u8be5\u9879\u521b\u65b0\u836f\u7269\u3002<\/p>\n\n\n\n<p><strong>1<\/strong>. <strong>\u5b97\u827e\u66ff\u5c3c\u4ece\u540e\u7ebf\u5230\u4e00\u7ebf<\/strong><\/p>\n\n\n\n<p><strong>2025\u5e748\u6708\uff1a\u540e\u7ebf\u6cbb\u7597\u4e2d\u7f8e\u53cc\u83b7\u6279<\/strong><\/p>\n\n\n\n<p>\u5b97\u827e\u66ff\u5c3c\uff08zongertinib\uff09\u4e8e2025\u5e748\u6708\u76f8\u7ee7\u83b7\u5f97\u7f8e\u56fdFDA\u548c\u4e2d\u56fd\u56fd\u5bb6\u836f\u76d1\u5c40\u6279\u51c6\u4e0a\u5e02\uff0c\u7528\u4e8e\u6cbb\u7597\u5b58\u5728HER2\u916a\u6c28\u9178\u6fc0\u9176\u7ed3\u6784\u57df\u6fc0\u6d3b\u7a81\u53d8\u4e14\u65e2\u5f80\u63a5\u53d7\u8fc7\u7cfb\u7edf\u6027\u6cbb\u7597\u7684\u4e0d\u53ef\u5207\u9664\u6216\u8f6c\u79fb\u6027\u975e\u9cde\u72b6\u975e\u5c0f\u7ec6\u80de\u80ba\u764c\u6210\u4eba\u60a3\u8005\u3002\u8fd9\u6807\u5fd7\u7740\u5168\u7403\u9996\u4e2a\u53e3\u670dHER2 TKI\u6b63\u5f0f\u8fdb\u5165\u4e34\u5e8a\u5b9e\u8df5\uff0c\u4e3a\u7ecf\u6cbb\u60a3\u8005\u63d0\u4f9b\u4e86\u5168\u65b0\u7684\u6cbb\u7597\u9009\u62e9\u3002<\/p>\n\n\n\n<p><strong>2026\u5e742\u6708\uff1a\u4e00\u7ebf\u6cbb\u7597\u518d\u7a81\u7834<\/strong><strong><\/strong><\/p>\n\n\n\n<p>2026\u5e742\u670826\u65e5\uff0cFDA\u901a\u8fc7\u201c\u5c40\u957f\u56fd\u5bb6\u4f18\u5148\u5ba1\u8bc4\u5238\u201d\u8bd5\u70b9\u9879\u76ee\uff0c\u4ec5\u752844\u5929\u52a0\u901f\u6279\u51c6\u5b97\u827e\u66ff\u5c3c\u7528\u4e8eHER2\u7a81\u53d8\u665a\u671f\u975e\u9cde\u72b6NSCLC\u7684\u4e00\u7ebf\u6cbb\u7597\u3002\u6b64\u6b21\u6279\u51c6\u5c06\u9002\u7528\u4eba\u7fa4\u4ece\u672a\u7ecf\u6cbb\u7597\u7684\u60a3\u8005\u6269\u5c55\u81f3\u521d\u6cbb\u60a3\u8005\uff0c\u5b8c\u6210\u4e86\u8be5\u836f\u5728HER2\u7a81\u53d8\u80ba\u764c\u6cbb\u7597\u4e2d\u7684\u5168\u9762\u5e03\u5c40\u3002<\/p>\n\n\n\n<p><strong>2<\/strong>. <strong>\u4f5c\u7528\u673a\u5236\uff1a\u9009\u62e9\u6027\u6291\u5236HER2<\/strong><\/p>\n\n\n\n<p>\u5b97\u827e\u66ff\u5c3c\uff08zongertinib\uff09\u662f\u4e00\u79cd\u65b0\u578b\u53e3\u670dHER2\u9009\u62e9\u6027\u916a\u6c28\u9178\u6fc0\u9176\u6291\u5236\u5242\uff0c\u5176\u72ec\u7279\u4e4b\u5904\u5728\u4e8e\u53ef\u4e0eHER2\u916a\u6c28\u9178\u6fc0\u9176\u7ed3\u6784\u57df\u5171\u4ef7\u7ed3\u5408\uff0c\u4e14\u4e0d\u5f71\u54cd\u91ce\u751f\u578b\u8868\u76ae\u751f\u957f\u56e0\u5b50\u53d7\u4f53\u3002<\/p>\n\n\n\n<p><strong>\u5b97\u827e\u66ff\u5c3c\u7684\u673a\u5236\u4f18\u52bf<\/strong><strong><\/strong><\/p>\n\n\n\n<p><strong>\u2022<\/strong><strong>&nbsp;<\/strong><strong>\u7cbe\u51c6\u9776\u5411\uff1a<\/strong>\u9009\u62e9\u6027\u6291\u5236HER2\uff08ERBB2\uff09\uff0c\u907f\u514d\u5bf9\u91ce\u751f\u578bEGFR\u7684\u6291\u5236<\/p>\n\n\n\n<p><strong>\u2022<\/strong><strong>&nbsp;<\/strong><strong>\u6bd2\u6027\u964d\u4f4e\uff1a<\/strong>\u6700\u5927\u7a0b\u5ea6\u51cf\u5c11\u4f20\u7edfEGFR\u6291\u5236\u5242\u5f15\u53d1\u7684\u76ae\u80a4\u6216\u80c3\u80a0\u9053\u4e0d\u826f\u53cd\u5e94<\/p>\n\n\n\n<p><strong>\u2022<\/strong><strong>&nbsp;<\/strong><strong>\u53e3\u670d\u4fbf\u5229\uff1a<\/strong>\u6bcf\u65e5\u4e00\u6b21\u7ed9\u836f\uff0c\u663e\u8457\u63d0\u5347\u60a3\u8005\u4f9d\u4ece\u6027\u548c\u751f\u6d3b\u8d28\u91cf<\/p>\n\n\n\n<p><strong>3<\/strong>. <strong>\u4e34\u5e8a\u6570\u636e\uff1a\u540e\u7ebf\u4e0e\u4e00\u7ebf\u7597\u6548\u4ff1\u4f73<\/strong><\/p>\n\n\n\n<p><strong>Beamion LUNG-1\u8bd5\u9a8c\u5173\u952e\u7ed3\u679c<\/strong><strong><\/strong><\/p>\n\n\n\n<p><strong>\u4e00\u7ebf\u6cbb\u7597\u6570\u636e\uff082026\u5e74FDA\u6279\u51c6\u4f9d\u636e\uff09\uff1a<\/strong><strong><\/strong><\/p>\n\n\n\n<p><strong>\u2022<\/strong><strong>&nbsp;<\/strong><strong>\u5ba2\u89c2\u7f13\u89e3\u7387\uff1a<\/strong>\u572872\u4f8b\u65e2\u5f80\u672a\u7ecf\u6cbb\u7597\u7684\u665a\u671fNSCLC\u60a3\u8005\u4e2d\uff0c\u7ecf\u786e\u8ba4\u7684\u5ba2\u89c2\u7f13\u89e3\u7387\u9ad8\u8fbe76%\uff0895%CI\uff1a65%-85%\uff09\u3002<\/p>\n\n\n\n<p><strong>\u2022<\/strong><strong>&nbsp;<\/strong><strong>\u7f13\u89e3\u6301\u7eed\u65f6\u95f4\uff1a<\/strong>64%\u7684\u7f13\u89e3\u60a3\u8005\u7f13\u89e3\u6301\u7eed\u65f6\u95f4\u8fbe\u52306\u4e2a\u6708\u53ca\u4ee5\u4e0a\uff0c44%\u8fbe\u523012\u4e2a\u6708\u53ca\u4ee5\u4e0a\u3002<\/p>\n\n\n\n<p><strong>\u5b89\u5168\u6027\u7279\u5f81<\/strong><strong><\/strong><\/p>\n\n\n\n<p>\u836f\u7269\u76f8\u5173\u4e0d\u826f\u53cd\u5e94\u53d1\u751f\u7387\u4e3a97%\uff0c\u22653\u7ea7\u4e0d\u826f\u53cd\u5e94\u53d1\u751f\u7387\u4e3a17%\u3002<\/p>\n\n\n\n<p>\u6700\u5e38\u89c1\u4e0d\u826f\u53cd\u5e94\u4e3a\u8179\u6cfb\uff0856%\uff09\uff0c\u65e0\u836f\u7269\u76f8\u5173\u6027\u95f4\u8d28\u6027\u80ba\u75c5\u75c5\u4f8b\u62a5\u544a\u3002<\/p>\n\n\n\n<p><strong>4<\/strong>. <strong>\u603b\u7ed3\u4e0e\u5c55\u671b<\/strong><\/p>\n\n\n\n<p>\u4ece2025\u5e748\u6708\u7684\u540e\u7ebf\u6cbb\u7597\u83b7\u6279\uff0c\u52302026\u5e742\u6708\u7684\u4e00\u7ebf\u6cbb\u7597\u6269\u5c55\uff0c\u5b97\u827e\u66ff\u5c3c\u5728\u77ed\u77ed\u534a\u5e74\u5185\u5b8c\u6210\u4e86\u6cbb\u7597\u683c\u5c40\u7684\u5168\u9762\u5e03\u5c40\u3002\u4f5c\u4e3a\u5168\u7403\u9996\u4e2a\u53e3\u670dHER2 TKI\uff0c\u5176\u9009\u62e9\u6027\u6291\u5236\u673a\u5236\u5e26\u6765\u7684\u5b89\u5168\u6027\u4f18\u52bf\uff0c\u52a0\u4e0a\u663e\u8457\u7684\u4e34\u5e8a\u7597\u6548\uff0c\u4f7f\u5176\u6210\u4e3aHER2\u7a81\u53d8\u975e\u5c0f\u7ec6\u80de\u80ba\u764c\u6cbb\u7597\u7684\u91cd\u8981\u7a81\u7834\u3002\u968f\u7740III\u671f\u786e\u8ba4\u8bd5\u9a8c\u7684\u63a8\u8fdb\u548c\u4e34\u5e8a\u5e94\u7528\u7684\u6269\u5927\uff0c\u5b97\u827e\u66ff\u5c3c\u6709\u671b\u91cd\u65b0\u5b9a\u4e49HER2\u9a71\u52a8\u578b\u80ba\u764c\u7684\u6cbb\u7597\u6807\u51c6\uff0c\u4e3a\u66f4\u591a\u60a3\u8005\u5e26\u6765\u751f\u5b58\u5e0c\u671b\u3002<\/p>\n\n\n<div class=\"wp-block-image\">\n<figure class=\"aligncenter size-full\"><img src=\"data:image\/gif;base64,R0lGODlhAQABAIAAAAAAAP\/\/\/yH5BAEAAAAALAAAAAABAAEAAAIBRAA7\" data-src=\"https:\/\/www.hkioc.com.hk\/wp-content\/uploads\/2026\/03\/\u56fe\u72472.png\" data-srcset=\"https:\/\/www.hkioc.com.hk\/wp-content\/uploads\/2026\/03\/\u56fe\u72472.png 609w, 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609px\"><\/noscript><\/figure><\/div>\n\n\n<p>\u8f6c\u8f7d\u8bf7\u8054\u7cfb\u6388\u6743\uff0c\u6216\u6ce8\u660e\u6765\u6e90\u3002<\/p>\n","protected":false},"excerpt":{"rendered":"<p>\u2022&nbsp;\u91cc\u7a0b\u7891\u610f\u4e49\uff1a\u5b97\u827e\u66ff\u5c3c\uff08zongertinib\uff09\u662f\u5168\u7403\u9996\u4e2a\u4e14\u76ee\u524d\u552f\u4e00\u83b7\u6279\u7684\u53e3\u670dHER2\u916a\u6c28\u9178\u6fc0\u9176\u6291<\/p>\n","protected":false},"author":14,"featured_media":38863,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[1747],"tags":[],"yst_prominent_words":[],"class_list":["post-38882","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-lung-cancer-zh-hans"],"_links":{"self":[{"href":"https:\/\/www.hkioc.com.hk\/zh-hans\/wp-json\/wp\/v2\/posts\/38882","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/www.hkioc.com.hk\/zh-hans\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/www.hkioc.com.hk\/zh-hans\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/www.hkioc.com.hk\/zh-hans\/wp-json\/wp\/v2\/users\/14"}],"replies":[{"embeddable":true,"href":"https:\/\/www.hkioc.com.hk\/zh-hans\/wp-json\/wp\/v2\/comments?post=38882"}],"version-history":[{"count":6,"href":"https:\/\/www.hkioc.com.hk\/zh-hans\/wp-json\/wp\/v2\/posts\/38882\/revisions"}],"predecessor-version":[{"id":38898,"href":"https:\/\/www.hkioc.com.hk\/zh-hans\/wp-json\/wp\/v2\/posts\/38882\/revisions\/38898"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/www.hkioc.com.hk\/zh-hans\/wp-json\/wp\/v2\/media\/38863"}],"wp:attachment":[{"href":"https:\/\/www.hkioc.com.hk\/zh-hans\/wp-json\/wp\/v2\/media?parent=38882"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/www.hkioc.com.hk\/zh-hans\/wp-json\/wp\/v2\/categories?post=38882"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/www.hkioc.com.hk\/zh-hans\/wp-json\/wp\/v2\/tags?post=38882"},{"taxonomy":"yst_prominent_words","embeddable":true,"href":"https:\/\/www.hkioc.com.hk\/zh-hans\/wp-json\/wp\/v2\/yst_prominent_words?post=38882"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}