{"id":40035,"date":"2026-06-09T17:21:58","date_gmt":"2026-06-09T09:21:58","guid":{"rendered":"https:\/\/www.hkioc.com.hk\/?p=40035"},"modified":"2026-06-10T15:09:18","modified_gmt":"2026-06-10T07:09:18","slug":"2026-asco%e9%87%8d%e7%a3%85%ef%bd%9c%e4%bb%8e%e4%b9%b3%e8%85%ba%e7%99%8c%e8%b5%b0%e5%90%91%e8%82%89%e7%98%a4%ef%bc%8c%e9%98%bf%e8%b4%9d%e8%a5%bf%e5%88%a9%e8%a1%a5%e9%bd%90%e5%8e%bb%e5%88%86%e5%8c%96","status":"publish","type":"post","link":"https:\/\/www.hkioc.com.hk\/zh-hans\/2026-asco%e9%87%8d%e7%a3%85%ef%bd%9c%e4%bb%8e%e4%b9%b3%e8%85%ba%e7%99%8c%e8%b5%b0%e5%90%91%e8%82%89%e7%98%a4%ef%bc%8c%e9%98%bf%e8%b4%9d%e8%a5%bf%e5%88%a9%e8%a1%a5%e9%bd%90%e5%8e%bb%e5%88%86%e5%8c%96\/","title":{"rendered":"2026 ASCO\u91cd\u78c5\uff5c\u4ece\u4e73\u817a\u764c\u8d70\u5411\u8089\u7624\uff0c\u963f\u8d1d\u897f\u5229\u8865\u9f50\u53bb\u5206\u5316\u8102\u80aa\u8089\u7624\u9776\u5411\u77ed\u677f"},"content":{"rendered":"\n

\u4e34\u5e8a\u4e2d\uff0c\u963f\u8d1d\u897f\u5229\uff08Abemaciclib\uff09\u4f5c\u4e3a\u7ecf\u5178CDK4\/6\u6291\u5236\u5242\uff0c\u5df2\u957f\u671f\u5e94\u7528\u4e8eHR\u9633\u6027\u665a\u671f\u4e73\u817a\u764c\u7684\u89c4\u8303\u5316\u6cbb\u7597\u3002\u57282026 ASCO\u5e74\u4f1a\u5168\u4f53\u5927\u4f1aLBA\u4e13\u573a<\/strong>\uff0c\u4e00\u9879\u540d\u4e3aSARC041\u7684\u5168\u7403\u2162\u671f\u4e34\u5e8a\u8bd5\u9a8c\u516c\u5e03\u5173\u952e\u7814\u7a76\u6570\u636e\uff0c\u8bc1\u5b9e\u8fd9\u6b3e\u4e73\u817a\u764c\u5e38\u7528\u836f\u7269\u5728\u53bb\u5206\u5316\u8102\u80aa\u8089\u7624\uff08Dedifferentiated liposarcoma\uff09<\/strong>\u9886\u57df\u5177\u5907\u660e\u786e\u6cbb\u7597\u4ef7\u503c\uff0c\u6210\u4e3a\u8be5\u7f55\u89c1\u8089\u7624\u9996\u4e2a\u53d6\u5f97\u9633\u6027\u2162\u671f\u7ed3\u679c\u7684\u9776\u5411\u836f\u7269\u3002<\/p>\n\n\n\n

1. \u53bb\u5206\u5316\u8102\u80aa\u8089\u7624\u4e34\u5e8a\u6cbb\u7597\u56f0\u5883<\/strong><\/strong><\/p>\n\n\n\n

\u53bb\u5206\u5316\u8102\u80aa\u8089\u7624\u662f\u4e34\u5e8a\u8f83\u4e3a\u5e38\u89c1\u7684\u6076\u6027\u8f6f\u7ec4\u7ec7\u8089\u7624\u4e9a\u578b\uff0c\u591a\u6570\u75c5\u7076\u539f\u53d1\u4e8e\u8179\u819c\u540e\u3001\u8179\u8154\u4f4d\u7f6e\uff0c\u75be\u75c5\u590d\u53d1\u7387\u9ad8\uff0c\u665a\u671f\u53d1\u751f\u8f6c\u79fb\u540e\u6cbb\u7597\u624b\u6bb5\u6709\u9650\u3002\u957f\u4e45\u4ee5\u6765\uff0c\u8be5\u7624\u79cd\u7f3a\u4e4f\u83b7\u6279\u7684\u9776\u5411\u6cbb\u7597\u836f\u7269\uff0c\u4e34\u5e8a\u4e3b\u8981\u4f9d\u9760\u4f20\u7edf\u5316\u7597\u8fdb\u884c\u7cfb\u7edf\u5e72\u9884\uff0c\u6574\u4f53\u7597\u6548\u6709\u9650\uff0c\u60a3\u8005\u5b58\u5728\u660e\u663e\u672a\u88ab\u6ee1\u8db3\u7684\u4e34\u5e8a\u9700\u6c42\u3002<\/p>\n\n\n\n

\u4ece\u836f\u7269\u673a\u7406\u6765\u770b\uff0cCDK4\/6\u901a\u8def\u5f02\u5e38\u6d3b\u5316\u662f\u9a71\u52a8\u53bb\u5206\u5316\u8102\u80aa\u8089\u7624\u589e\u6b96\u7684\u5173\u952e\u56e0\u7d20\uff0c\u800c\u963f\u8d1d\u897f\u5229\u901a\u8fc7\u9009\u62e9\u6027\u6291\u5236CDK4\/6\u9776\u70b9\u963b\u6ede\u80bf\u7624\u7ec6\u80de\u5468\u671f\uff0c\u65e2\u5f80\u83b7\u6279\u9002\u5e94\u75c7\u805a\u7126HR\u9633\u6027\u3001HER2\u9634\u6027\u4e73\u817a\u764c\uff0c\u57fa\u4e8e\u9776\u70b9\u673a\u5236\uff0c\u7814\u7a76\u8005\u5f00\u5c55\u8de8\u7624\u79cd\u2162\u671fSARC041\u4e34\u5e8a\u8bd5\u9a8c\u3002<\/p>\n\n\n\n

2. \u53bb\u5206\u5316\u8102\u80aa\u8089\u7624\u4e34\u5e8a\u6cbb\u7597\u56f0\u5883<\/strong><\/strong><\/p>\n\n\n\n

SARC041\u4e3a\u5168\u7403\u591a\u4e2d\u5fc3\u3001\u968f\u673a\u3001\u53cc\u76f2\u3001\u5b89\u6170\u5242\u5bf9\u7167\u2162\u671f\u4e34\u5e8a\u8bd5\u9a8c\uff08NCT04967521\uff09\uff0c\u7814\u7a76\u5165\u7ec4\u7ecf\u5f71\u50cf\u5b66\u786e\u8ba4\u75be\u75c5\u8fdb\u5c55\u7684\u590d\u53d1\u6216\u8f6c\u79fb\u6027\u53bb\u5206\u5316\u8102\u80aa\u8089\u7624\u6210\u5e74\u60a3\u8005\uff0c\u53d7\u8bd5\u8005\u6309\u71671:1\u6bd4\u4f8b\u968f\u673a\u5206\u7ec4\uff0c\u5206\u5c42\u6807\u51c6\u4ee5\u53d7\u8bd5\u8005\u65e2\u5f80\u662f\u5426\u63a5\u53d7\u8fc7\u5168\u8eab\u7cfb\u7edf\u6cbb\u7597\u8fdb\u884c\u5212\u5206\uff0c\u4e24\u7ec4\u5404\u5165\u7ec454\u4f8b\u53d7\u8bd5\u8005\u3002<\/p>\n\n\n\n

1. \u7528\u836f\u65b9\u6848<\/strong><\/strong><\/p>\n\n\n\n

\u2022 \u963f\u8d1d\u897f\u5229\u7ec4\uff1a<\/strong>200mg\uff0c\u6bcf\u65e5\u4e24\u6b21\u53e3\u670d\uff0c\u6301\u7eed\u7528\u836f\u76f4\u81f3\u75be\u75c5\u8fdb\u5c55\u3001\u4e0d\u53ef\u8010\u53d7\u4e0d\u826f\u53cd\u5e94\u6216\u53d7\u8bd5\u8005\u9000\u51fa\u7814\u7a76\uff1b<\/p>\n\n\n\n

\u2022 \u5b89\u6170\u5242\u7ec4\uff1a<\/strong>\u5339\u914d\u5242\u578b\u5b89\u6170\u5242\uff0c\u670d\u7528\u89c4\u5219\u540c\u8bd5\u9a8c\u7ec4\uff1b\u53d7\u8bd5\u8005\u51fa\u73b0\u75be\u75c5\u8fdb\u5c55\u540e\uff0c\u53ef\u8de8\u7ec4\u8f6c\u5165\u963f\u8d1d\u897f\u5229\u6cbb\u7597\uff0c\u6700\u7ec885%\u5b89\u6170\u5242\u7ec4\u60a3\u8005\u5728\u8fdb\u5c55\u540e\u4ea4\u53c9\u6362\u836f\u3002<\/p>\n\n\n\n

2. \u7597\u6548\u4e0e\u5b89\u5168\u8bc4\u4f30<\/strong><\/strong><\/p>\n\n\n\n

\u2022 \u524d36\u5468\u6bcf6\u5468\u901a\u8fc7\u5f71\u50cf\u5b66\u590d\u67e5\u8bc4\u4f30\u80bf\u7624\u53d8\u5316\uff0c36\u5468\u540e\u8c03\u6574\u4e3a\u6bcf12\u5468\u590d\u67e5\uff1b\u4e0d\u826f\u53cd\u5e94\u4f9d\u636e\u901a\u7528\u4e0d\u826f\u4e8b\u4ef6\u8bc4\u4ef7\u6807\u51c6\u5206\u7ea7\u8bb0\u5f55\u3002\u7814\u7a76\u4e3b\u8981\u7ec8\u70b9\u8bbe\u5b9a\u4e3a\u65e0\u8fdb\u5c55\u751f\u5b58\u671f\uff08PFS\uff09\uff0c\u6b21\u8981\u7ec8\u70b9\u5305\u542b\u5ba2\u89c2\u7f13\u89e3\u7387\u3001\u603b\u751f\u5b58\u671f\u3001\u7528\u836f\u5b89\u5168\u6027\u3002<\/p>\n\n\n\n

\u2022 \u57fa\u7ebf\u8d44\u6599\u663e\u793a\uff0c\u53d7\u8bd5\u8005\u4e2d\u4f4d\u5e74\u9f8467\u5c81\uff0c\u7edd\u5927\u591a\u6570\u80bf\u7624\u539f\u53d1\u7076\u4f4d\u4e8e\u8179\u8154\u4e0e\u8179\u819c\u540e\uff0c\u4e24\u7ec4\u521d\u6cbb\u3001\u591a\u7ebf\u7ecf\u6cbb\u60a3\u8005\u5360\u6bd4\u5747\u8861\uff0c\u57fa\u7ebf\u6570\u636e\u5177\u5907\u53ef\u6bd4\u6027\u3002<\/p>\n\n\n\n

3. \u4e34\u5e8a\u8bd5\u9a8c\u6838\u5fc3\u7814\u7a76\u6570\u636e<\/strong><\/strong><\/p>\n\n\n\n

1. \u65e0\u8fdb\u5c55\u751f\u5b58\u671f\uff08\u4e3b\u8981\u7814\u7a76\u7ec8\u70b9\uff09<\/strong><\/strong><\/p>\n\n\n\n

\u963f\u8d1d\u897f\u5229\u7ec4\u4e2d\u4f4d\u65e0\u8fdb\u5c55\u751f\u5b58\u671f9.7\u4e2a\u6708\uff0c\u5b89\u6170\u5242\u7ec4\u4e3a1.5\u4e2a\u6708\uff0cHR=0.38\uff08P\uff1c0.001\uff09\uff0c\u53ef\u4f7f\u60a3\u8005\u75be\u75c5\u8fdb\u5c55\u4e0e\u6b7b\u4ea1\u98ce\u9669\u4e0b\u964d62%\u3002\u8fdc\u671f\u9636\u6bb5\u6027\u751f\u5b58\u6570\u636e\uff1a\u7528\u836f\u7ec46\u4e2a\u6708\u65e0\u8fdb\u5c55\u751f\u5b58\u738760%\u300112\u4e2a\u6708\u65e0\u8fdb\u5c55\u751f\u5b58\u738739%\uff1b\u5b89\u6170\u5242\u7ec4\u5bf9\u5e94\u6570\u636e\u5206\u522b\u4e3a22%\u300113%\u3002<\/p>\n\n\n\n

\u4e9a\u7ec4\u5206\u6790\uff1a\u65e2\u5f80\u672a\u63a5\u53d7\u5168\u8eab\u6cbb\u7597\u7684\u521d\u6cbb\u60a3\u8005\u4e2d\u4f4dPFS\u53ef\u8fbe16.4\u4e2a\u6708\uff0c\u63a5\u53d7\u8fc7\u591a\u7ebf\u6cbb\u7597\u60a3\u8005\u4e2d\u4f4dPFS5.3\u4e2a\u6708\uff0c\u63d0\u793a\u60a3\u8005\u8d8a\u65e9\u542f\u7528\u836f\u7269\uff0c\u4e34\u5e8a\u83b7\u76ca\u8d8a\u7a81\u51fa\u3002<\/p>\n\n\n\n

2. \u603b\u751f\u5b58\u671f<\/strong><\/strong><\/p>\n\n\n\n

\u53d7\u5b89\u6170\u5242\u7ec4\u8d85\u9ad8\u4ea4\u53c9\u6362\u836f\u7387\u5f71\u54cd\uff0c\u603b\u751f\u5b58\u671f\u6682\u672a\u8fbe\u5230\u7edf\u8ba1\u5b66\u663e\u8457\u5dee\u5f02\uff0c\u4f46\u751f\u5b58\u83b7\u76ca\u8d8b\u52bf\u660e\u786e\uff1a\u963f\u8d1d\u897f\u5229\u7ec4\u4e2d\u4f4d\u603b\u751f\u5b58\u671f\u5c1a\u672a\u62b5\u8fbe\uff0c\u5b89\u6170\u5242\u7ec4\u4e2d\u4f4dOS25.5\u4e2a\u6708\uff1b12\u4e2a\u6708OS\u738785% vs 71%\uff0c24\u4e2a\u6708OS\u738772% vs 51%\u3002\u5b89\u6170\u5242\u7ec4\u53d7\u8bd5\u8005\u8fdb\u5c55\u540e\u6362\u7528\u963f\u8d1d\u897f\u5229\uff0c\u5176\u4e2d\u4f4dPFS\u4ec53.\u4e2a\u6708\uff0c\u4f4e\u4e8e\u4e00\u7ebf\u76f4\u63a5\u7528\u836f\u6570\u636e\u3002<\/p>\n\n\n\n

3. \u5ba2\u89c2\u7f13\u89e3\u4e0e\u75be\u75c5\u63a7\u5236<\/strong><\/strong><\/p>\n\n\n\n

\u963f\u8d1d\u897f\u5229\u7ec4\u5ba2\u89c2\u7f13\u89e3\u73879%\uff0c\u5b89\u6170\u5242\u7ec4\u65e0\u5ba2\u89c2\u7f13\u89e3\u75c5\u4f8b\uff1b\u8be5\u836f\u7269\u4f5c\u7528\u7279\u70b9\u4ee5\u7a33\u5b9a\u80bf\u7624\u75c5\u7076\u4e3a\u4e3b\uff0c\u75c5\u7076\u7f29\u5c0f\u6bd4\u4f8b\u504f\u4f4e\uff0c\u662fCDK4\/6\u6291\u5236\u5242\u7684\u56fa\u6709\u4e34\u5e8a\u7279\u5f81\u3002\u5b89\u6170\u5242\u4ea4\u53c9\u540e\u6362\u7528\u963f\u8d1d\u897f\u5229\u7684\u53d7\u8bd5\u8005\u5ba2\u89c2\u7f13\u89e3\u7387\u4ec54%\u3002<\/p>\n\n\n\n

4. \u5b89\u5168\u6027\u8868\u73b0<\/strong><\/strong><\/p>\n\n\n\n

\u963f\u8d1d\u897f\u5229\u7ec439%\u53d7\u8bd5\u8005\u56e0\u4e0d\u826f\u53cd\u5e94\u9700\u8981\u4e0b\u8c03\u7528\u836f\u5242\u91cf\uff0c\u5b89\u6170\u5242\u7ec4\u4ec52%\u53d7\u8bd5\u8005\u51fa\u73b0\u5242\u91cf\u8c03\u6574\u3002\u836f\u7269\u5e38\u89c1\u6cbb\u7597\u76f8\u5173\u4e0d\u826f\u53cd\u5e94\u4e3a\u8179\u6cfb\u3001\u8d2b\u8840\u3001\u4e2d\u6027\u7c92\u7ec6\u80de\u51cf\u5c11\u3001\u767d\u7ec6\u80de\u4e0b\u964d\u7b49\uff0c\u4e0d\u826f\u53cd\u5e94\u5206\u7ea7\u591a\u96c6\u4e2d\u57281~2\u7ea7\uff0c\u91cd\u5ea6\u4e0d\u826f\u53cd\u5e94\u53d1\u751f\u7387\u53ef\u63a7\uff0c\u6574\u4f53\u5b89\u5168\u8c31\u548c\u5176\u5728\u4e73\u817a\u764c\u4e34\u5e8a\u5e94\u7528\u4e2d\u7684\u4e0d\u826f\u53cd\u5e94\u8868\u73b0\u4fdd\u6301\u4e00\u81f4\u3002<\/p>\n\n\n\n

4. \u4e34\u5e8a\u4ef7\u503c\u4e0e\u7814\u7a76\u5c40\u9650\u6027<\/strong><\/strong><\/p>\n\n\n\n

\u4e34\u5e8a\u610f\u4e49<\/strong><\/strong><\/p>\n\n\n\n

1. SARC041\u662f\u53bb\u5206\u5316\u8102\u80aa\u8089\u7624\u9886\u57df\u9996\u9879\u53d6\u5f97\u9633\u6027\u7ed3\u679c\u7684\u2162\u671f\u9776\u5411\u4e34\u5e8a\u8bd5\u9a8c\uff0c\u7ed3\u675f\u8be5\u4e9a\u578b\u8089\u7624\u65e0\u2162\u671f\u4e34\u5e8a\u4f50\u8bc1\u9776\u5411\u836f\u7684\u73b0\u72b6\uff1b<\/p>\n\n\n\n

2. \u5b9e\u73b0\u963f\u8d1d\u897f\u5229\u4ece\u4e73\u817a\u764c\u9002\u5e94\u75c7\u5411\u8f6f\u7ec4\u7ec7\u8089\u7624\u7684\u8de8\u7624\u79cd\u4e34\u5e8a\u843d\u5730\uff0c\u4e3aDDLS\u60a3\u8005\u65b0\u589e\u9776\u5411\u6cbb\u7597\u9009\u62e9\uff1b<\/p>\n\n\n\n

3. \u4e9a\u7ec4\u6570\u636e\u63d0\u793a\u65e9\u671f\u7528\u836f\u83b7\u76ca\u66f4\u4f73\uff0c\u4e3a\u540e\u7eed\u56f4\u624b\u672f\u671f\u65b0\u8f85\u52a9\u3001\u8f85\u52a9\u6cbb\u7597\u4e34\u5e8a\u8bd5\u9a8c\u63d0\u4f9b\u5faa\u8bc1\u4f9d\u636e\u3002<\/p>\n\n\n\n

\u7814\u7a76\u5c40\u9650<\/strong><\/strong><\/p>\n\n\n\n

1. \u5b89\u6170\u5242\u7ec485%\u53d7\u8bd5\u8005\u8fdb\u5c55\u540e\u4ea4\u53c9\u7528\u836f\uff0c\u5e72\u6270\u603b\u751f\u5b58\u671f\u6570\u636e\u7edf\u8ba1\uff0c\u96be\u4ee5\u89c2\u6d4b\u7eaf\u5b89\u6170\u5242\u957f\u671f\u751f\u5b58\u6570\u636e\uff1b<\/p>\n\n\n\n

2. \u5355\u7ec4\u5165\u7ec4\u6837\u672c\u91cf54\u4f8b\uff0c\u7f55\u89c1\u57fa\u56e0\u7a81\u53d8\u4e9a\u7ec4\u6837\u672c\u504f\u5c11\uff1b<\/p>\n\n\n\n

3. \u836f\u7269\u5ba2\u89c2\u7f13\u89e3\u7387\u504f\u4f4e\uff0c\u5bf9\u9700\u8981\u5feb\u901f\u7f29\u5c0f\u80bf\u7624\u75c5\u7076\u7684\u5feb\u901f\u8fdb\u5c55\u60a3\u8005\u9002\u7528\u6027\u6709\u9650\uff1b<\/p>\n\n\n\n

4. 5\u5e74\u957f\u671f\u751f\u5b58\u968f\u8bbf\u4ecd\u5728\u6301\u7eed\u8fdb\u884c\uff0c\u8fdc\u671f\u751f\u5b58\u6570\u636e\u5c1a\u672a\u6210\u719f\u3002<\/p>\n\n\n\n

5<\/strong>. <\/strong>\u540e\u7eed\u7814\u53d1\u89c4\u5212<\/strong><\/strong><\/p>\n\n\n\n

\u57fa\u4e8e\u672c\u6b21SARC041\u2162\u671f\u9633\u6027\u6570\u636e\uff0c\u836f\u4f01\u8ba1\u5212\u5411FDA\u9012\u4ea4\u963f\u8d1d\u897f\u5229\u7528\u4e8e\u590d\u53d1\/\u8f6c\u79fb\u6027\u53bb\u5206\u5316\u8102\u80aa\u8089\u7624\u7684\u65b0\u589e\u9002\u5e94\u75c7\u4e0a\u5e02\u7533\u8bf7\uff1b\u4e0e\u6b64\u540c\u65f6\uff0c\u76f8\u5173\u751f\u7269\u6807\u5fd7\u7269\u63a2\u7d22\u3001\u56f4\u624b\u672f\u671f\u65b0\u8f85\u52a9\/\u8f85\u52a9\u6cbb\u7597\u2162\u671f\u4e34\u5e8a\u8bd5\u9a8c\u6b63\u5728\u6709\u5e8f\u63a8\u8fdb\u3002<\/p>\n\n\n\n

\u8f6c\u8f7d\u8bf7\u8054\u7cfb\u6388\u6743\uff0c\u6216\u6ce8\u660e\u6765\u6e90<\/p>\n","protected":false},"excerpt":{"rendered":"

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