{"id":40349,"date":"2026-06-24T14:54:47","date_gmt":"2026-06-24T06:54:47","guid":{"rendered":"https:\/\/www.hkioc.com.hk\/?p=40349"},"modified":"2026-06-24T14:57:32","modified_gmt":"2026-06-24T06:57:32","slug":"fda%e6%89%b9%e5%87%86belzutifan%e8%81%94%e5%90%88pembrolizumab%e7%94%a8%e4%ba%8e%e9%ab%98%e5%a4%8d%e5%8f%91%e9%a3%8e%e9%99%a9%e9%80%8f%e6%98%8e%e7%bb%86%e8%83%9e%e8%82%be%e7%bb%86%e8%83%9e%e7%99%8c","status":"publish","type":"post","link":"https:\/\/www.hkioc.com.hk\/zh-hans\/fda%e6%89%b9%e5%87%86belzutifan%e8%81%94%e5%90%88pembrolizumab%e7%94%a8%e4%ba%8e%e9%ab%98%e5%a4%8d%e5%8f%91%e9%a3%8e%e9%99%a9%e9%80%8f%e6%98%8e%e7%bb%86%e8%83%9e%e8%82%be%e7%bb%86%e8%83%9e%e7%99%8c\/","title":{"rendered":"FDA\u6279\u51c6Belzutifan\u8054\u5408Pembrolizumab\u7528\u4e8e\u9ad8\u590d\u53d1\u98ce\u9669\u900f\u660e\u7ec6\u80de\u80be\u7ec6\u80de\u764c\u672f\u540e\u8f85\u52a9\u6cbb\u7597"},"content":{"rendered":"\n

2026\u5e746\u670812\u65e5\uff0c\u7f8e\u56fd\u98df\u54c1\u836f\u54c1\u76d1\u7763\u7ba1\u7406\u5c40\uff08FDA\uff09\u6279\u51c6Belzutifan\u8054\u5408Pembrolizumab\uff0c\u7528\u4e8e\u6210\u4eba\u900f\u660e\u7ec6\u80de\u80be\u7ec6\u80de\u764c\uff08ccRCC\uff09\u60a3\u8005\u7684\u672f\u540e\u8f85\u52a9\u6cbb\u7597\u3002<\/p>\n\n\n\n

\u6b64\u6b21\u9002\u7528\u4eba\u7fa4\u4e3a\uff1a\u63a5\u53d7\u80be\u5207\u9664\u672f\u540e\uff0c\u5c5e\u4e8e\u4e2d\u9ad8\u5371\u6216\u9ad8\u5371\u590d\u53d1\u98ce\u9669\u7684\u900f\u660e\u7ec6\u80de\u80be\u7ec6\u80de\u764c\u60a3\u8005\uff1b\u6216\u63a5\u53d7\u80be\u5207\u9664\u672f\u5e76\u5b8c\u6210\u8f6c\u79fb\u75c5\u7076\u5207\u9664\u540e\uff0c\u76ee\u524d\u65e0\u75be\u75c5\u8bc1\u636e\u4f46\u4ecd\u5b58\u5728\u8f83\u9ad8\u590d\u53d1\u98ce\u9669\u7684\u60a3\u8005\u3002\u5bf9\u4e8e\u9002\u5408\u76ae\u4e0b\u6ce8\u5c04\u7ed9\u836f\u7684\u60a3\u8005\uff0c\u4e5f\u53ef\u91c7\u7528Pembrolizumab\u4e0eberahyaluronidase alfa-pmph\u590d\u65b9\u5236\u5242\u8054\u5408Belzutifan\u7684\u65b9\u6848\u3002<\/p>\n\n\n\n

\u8fd9\u4e00\u6279\u51c6\u610f\u5473\u7740\uff0c\u9ad8\u590d\u53d1\u98ce\u9669\u900f\u660e\u7ec6\u80de\u80be\u7ec6\u80de\u764c\u60a3\u8005\u5728\u624b\u672f\u540e\uff0c\u9664\u65e2\u6709\u514d\u75ab\u6cbb\u7597\u9009\u62e9\u5916\uff0c\u65b0\u589e\u4e86\u4e00\u79cd\u7531PD-1\u6291\u5236\u5242\u4e0eHIF-2\u03b1\u6291\u5236\u5242\u7ec4\u6210\u7684\u8f85\u52a9\u6cbb\u7597\u65b9\u6848\u3002<\/p>\n\n\n\n

1. <\/strong>\u4e3a\u4ec0\u4e48\u80be\u764c\u672f\u540e\u4ecd\u9700\u8981\u8f85\u52a9\u6cbb\u7597\uff1f<\/strong><\/strong><\/p>\n\n\n\n

\u80be\u7ec6\u80de\u764c\uff08RCC\uff09\u662f\u6700\u5e38\u89c1\u7684\u80be\u764c\u7c7b\u578b\uff0c\u7ea6\u5360\u80be\u764c\u8bca\u65ad\u7684\u4e5d\u6210\u3002\u900f\u660e\u7ec6\u80de\u80be\u7ec6\u80de\u764c\u662f\u5176\u4e2d\u6700\u5e38\u89c1\u7684\u4e9a\u578b\uff0c\u7ea6\u5360\u80be\u7ec6\u80de\u764c\u768475%\u3002<\/p>\n\n\n\n

\u5bf9\u4e8e\u5c40\u90e8\u6216\u5c40\u90e8\u8fdb\u5c55\u671f\u900f\u660e\u7ec6\u80de\u80be\u7ec6\u80de\u764c\uff0c\u624b\u672f\u5207\u9664\u4ecd\u662f\u91cd\u8981\u6cbb\u7597\u65b9\u5f0f\u3002\u7136\u800c\uff0c\u624b\u672f\u5e76\u4e0d\u610f\u5473\u7740\u6240\u6709\u60a3\u8005\u90fd\u80fd\u5f7b\u5e95\u8fdc\u79bb\u590d\u53d1\u98ce\u9669\u3002\u90e8\u5206\u4e2d\u9ad8\u5371\u6216\u9ad8\u5371\u60a3\u8005\u5373\u4f7f\u5df2\u7ecf\u5b8c\u6210\u80bf\u7624\u5207\u9664\uff0c\u540e\u7eed\u4ecd\u53ef\u80fd\u51fa\u73b0\u75be\u75c5\u590d\u53d1\uff0c\u751a\u81f3\u53d1\u5c55\u4e3a\u8f6c\u79fb\u6027\u75be\u75c5\u3002\u5bf9\u4e8e\u90e8\u5206\u4e2d\u9ad8\u5371\u6216\u9ad8\u5371\u60a3\u8005\u800c\u8a00\uff0c\u5373\u4f7f\u5df2\u7ecf\u5b8c\u6210\u80bf\u7624\u5207\u9664\uff0c\u672f\u540e\u4ecd\u5b58\u5728\u75be\u75c5\u590d\u53d1\u7684\u53ef\u80fd\u3002\u56e0\u6b64\uff0c\u5982\u4f55\u5728\u672f\u540e\u9636\u6bb5\u8fdb\u4e00\u6b65\u964d\u4f4e\u590d\u53d1\u98ce\u9669\uff0c\u4e00\u76f4\u662f\u80be\u764c\u6cbb\u7597\u9886\u57df\u6301\u7eed\u5173\u6ce8\u7684\u91cd\u8981\u95ee\u9898\u3002<\/p>\n\n\n\n

\u8f85\u52a9\u6cbb\u7597\u7684\u76ee\u7684\uff0c\u6b63\u662f\u5728\u624b\u672f\u540e\u3001\u5f71\u50cf\u5b66\u53ef\u80fd\u6682\u65f6\u770b\u4e0d\u5230\u660e\u786e\u75c5\u7076\u7684\u9636\u6bb5\uff0c\u901a\u8fc7\u7cfb\u7edf\u6cbb\u7597\u5c3d\u53ef\u80fd\u6e05\u9664\u6f5c\u5728\u5fae\u5c0f\u6b8b\u7559\u75c5\u7076\uff0c\u5ef6\u7f13\u6216\u51cf\u5c11\u590d\u53d1\u53d1\u751f\u3002<\/p>\n\n\n\n

2. <\/strong>3\u671fLITESPARK-022\u7814\u7a76<\/strong><\/p>\n\n\n\n

\u6b64\u6b21FDA\u6279\u51c6\u4e3b\u8981\u57fa\u4e8e3\u671fLITESPARK-022\u7814\u7a76\u6570\u636e\u3002LITESPARK-022\u662f\u4e00\u9879\u591a\u4e2d\u5fc3\u3001\u53cc\u76f2\u3001\u968f\u673a\u4e34\u5e8a\u8bd5\u9a8c\uff0c\u5171\u7eb3\u51651841\u4f8b\u65e2\u5f80\u63a5\u53d7\u900f\u660e\u7ec6\u80de\u80be\u7ec6\u80de\u764c\u80be\u5207\u9664\u672f\u7684\u60a3\u8005\u3002\u8fd9\u4e9b\u60a3\u8005\u5c5e\u4e8e\u4e2d\u9ad8\u5371\u6216\u9ad8\u5371\u590d\u53d1\u98ce\u9669\u4eba\u7fa4\uff0c\u6216\u5df2\u5b8c\u6210\u8f6c\u79fb\u75c5\u7076\u5207\u9664\u4e14\u65e0\u75be\u75c5\u8bc1\u636e\u3002<\/p>\n\n\n\n

\u201c\u591a\u4e2d\u5fc3\u201d\u610f\u5473\u7740\u7814\u7a76\u5728\u591a\u5bb6\u533b\u7597\u673a\u6784\u540c\u6b65\u5f00\u5c55\uff1b\u201c\u968f\u673a\u201d\u610f\u5473\u7740\u60a3\u8005\u88ab\u5206\u914d\u81f3\u4e0d\u540c\u6cbb\u7597\u7ec4\u7684\u8fc7\u7a0b\u5177\u6709\u968f\u673a\u6027\uff1b\u201c\u53cc\u76f2\u201d\u5219\u8868\u793a\u60a3\u8005\u548c\u7814\u7a76\u533b\u751f\u5747\u4e0d\u77e5\u9053\u5177\u4f53\u63a5\u53d7\u7684\u662f\u8bd5\u9a8c\u836f\u7269\u8fd8\u662f\u5bf9\u7167\u65b9\u6848\u3002\u8fd9\u79cd\u8bbe\u8ba1\u6709\u52a9\u4e8e\u51cf\u5c11\u4e3b\u89c2\u504f\u501a\uff0c\u4f7f\u7814\u7a76\u7ed3\u679c\u66f4\u5177\u53ef\u9760\u6027\u3002<\/p>\n\n\n\n

\u7814\u7a76\u4e2d\uff0c1841\u4f8b\u60a3\u8005\u63091:1\u6bd4\u4f8b\u968f\u673a\u5206\u7ec4\uff1a<\/strong><\/p>\n\n\n\n

\u4e00\u7ec4\u63a5\u53d7Belzutifan\u8054\u5408Pembrolizumab\u4f5c\u4e3a\u8f85\u52a9\u6cbb\u7597\uff1b<\/p>\n\n\n\n

\u53e6\u4e00\u7ec4\u63a5\u53d7\u5b89\u6170\u5242\u8054\u5408Pembrolizumab\u6cbb\u7597\u3002<\/p>\n\n\n\n

\u6cbb\u7597\u6301\u7eed\u81f3\u75be\u75c5\u590d\u53d1\u3001\u51fa\u73b0\u65e0\u6cd5\u8010\u53d7\u7684\u6bd2\u6027\u53cd\u5e94\uff0c\u6216\u8fbe\u5230\u65b9\u6848\u89c4\u5b9a\u7684\u6700\u957f\u6cbb\u7597\u65f6\u95f4\uff1aBelzutifan\u6700\u957f54\u5468\uff0cPembrolizumab\u6700\u957f12\u4e2a\u6708\u3002<\/p>\n\n\n\n

\u8be5\u7814\u7a76\u7684\u4e3b\u8981\u7597\u6548\u7ec8\u70b9\u4e3a\u7814\u7a76\u8005\u8bc4\u4f30\u7684\u65e0\u75c5\u751f\u5b58\u671f\uff08DFS\uff09\uff0c\u5373\u4ece\u968f\u673a\u5206\u7ec4\u5230\u75be\u75c5\u590d\u53d1\u3001\u53d1\u751f\u8f6c\u79fb\u6216\u6b7b\u4ea1\u7684\u65f6\u95f4\u3002\u6b21\u8981\u7ec8\u70b9\u5305\u62ec\u603b\u751f\u5b58\u671f\uff08OS\uff09\u548c\u5b89\u5168\u6027\u3002<\/p>\n\n\n\n

3. <\/strong>\u8054\u5408\u6cbb\u7597\u663e\u8457\u5ef6\u957f\u65e0\u75c5\u751f\u5b58\u671f<\/strong><\/p>\n\n\n\n

\u7814\u7a76\u7ed3\u679c\u663e\u793a\uff0c\u4e0e\u5b89\u6170\u5242\u8054\u5408Pembrolizumab\u76f8\u6bd4\uff0cBelzutifan\u8054\u5408Pembrolizumab\u663e\u8457\u6539\u5584\u4e86\u65e0\u75c5\u751f\u5b58\u671f\u3002\u5728\u9884\u8bbe\u4e2d\u671f\u5206\u6790\u4e2d\uff0cBelzutifan\u8054\u5408Pembrolizumab\u7ec4\u6709186\u4f8b\u60a3\u8005\u51fa\u73b0\u75be\u75c5\u590d\u53d1\u3001\u53d1\u751f\u8f6c\u79fb\u6216\u6b7b\u4ea1\uff1b\u5bf9\u7167\u7ec4\u4e3a246\u4f8b\u3002\u7814\u7a76\u663e\u793a\uff0c\u4e0e\u5bf9\u7167\u7ec4\u76f8\u6bd4\uff0c\u8054\u5408\u6cbb\u7597\u5c06\u590d\u53d1\u3001\u8f6c\u79fb\u6216\u6b7b\u4ea1\u98ce\u9669\u964d\u4f4e\u7ea628%\u3002<\/p>\n\n\n\n

\u5bf9\u4e8e\u5927\u4f17\u8bfb\u8005\u800c\u8a00\uff0c\u53ef\u4ee5\u8fd9\u6837\u7406\u89e3\uff1a\u5728\u7814\u7a76\u968f\u8bbf\u671f\u95f4\uff0c\u4e0e\u5355\u7528Pembrolizumab\u76f8\u6bd4\uff0c\u52a0\u5165Belzutifan\u540e\uff0c\u60a3\u8005\u51fa\u73b0\u590d\u53d1\u3001\u8f6c\u79fb\u6216\u6b7b\u4ea1\u7684\u98ce\u9669\u8fdb\u4e00\u6b65\u4e0b\u964d\u3002<\/p>\n\n\n\n

\u9700\u8981\u6ce8\u610f\u7684\u662f\uff0c\u622a\u81f3\u5206\u6790\u65f6\uff0c\u4e24\u7ec4\u7684\u4e2d\u4f4d\u65e0\u75c5\u751f\u5b58\u671f\u5747\u5c1a\u672a\u8fbe\u5230\u3002\u8fd9\u610f\u5473\u7740\u5728\u5f53\u524d\u968f\u8bbf\u65f6\u95f4\u5185\uff0c\u4e24\u7ec4\u4e2d\u53d1\u751f\u590d\u53d1\u3001\u8f6c\u79fb\u6216\u6b7b\u4ea1\u4e8b\u4ef6\u7684\u60a3\u8005\u6bd4\u4f8b\u5c1a\u672a\u8d85\u8fc7\u4e00\u534a\uff0c\u56e0\u6b64\u8fd8\u65e0\u6cd5\u8ba1\u7b97\u51fa\u4e2d\u4f4d\u65e0\u75c5\u751f\u5b58\u671f\u3002<\/p>\n\n\n\n

\u5728\u603b\u751f\u5b58\u671f\u65b9\u9762\uff0cOS\u6570\u636e\u5728\u9884\u8bbe\u4e2d\u671f\u5206\u6790\u65f6\u5c1a\u672a\u6210\u719f\uff0c\u56e0\u6b64\u76ee\u524d\u5c1a\u4e0d\u80fd\u5224\u65ad\u8be5\u8054\u5408\u65b9\u6848\u662f\u5426\u5df2\u7ecf\u5e26\u6765\u660e\u786e\u7684\u603b\u751f\u5b58\u83b7\u76ca\u3002<\/p>\n\n\n\n

4. <\/strong>24\u4e2a\u6708\u65f6\uff0c\u8054\u5408\u6cbb\u7597\u7ec4\u65e0\u75c5\u751f\u5b58\u7387\u66f4\u9ad8<\/strong><\/p>\n\n\n\n

\u57282026\u5e74\u6ccc\u5c3f\u751f\u6b96\u7cfb\u7edf\u80bf\u7624\u7814\u8ba8\u4f1a\u671f\u95f4\u516c\u5e03\u7684\u8fdb\u4e00\u6b65\u6570\u636e\u4e2d\uff0c\u7814\u7a76\u62a5\u544a\u4e86\u4e0d\u540c\u65f6\u95f4\u70b9\u7684\u65e0\u75c5\u751f\u5b58\u7387\u548c\u603b\u751f\u5b58\u7387\u3002<\/p>\n\n\n\n

\u5728\u610f\u5411\u6cbb\u7597\u4eba\u7fa4\u4e2d\uff0cBelzutifan\u8054\u5408Pembrolizumab\u7ec412\u4e2a\u6708\u300124\u4e2a\u6708\u548c30\u4e2a\u6708\u7684\u65e0\u75c5\u751f\u5b58\u7387\u5206\u522b\u4e3a91.9%\u300180.7%\u548c75.8%\uff1bPembrolizumab\u8054\u5408\u5b89\u6170\u5242\u7ec4\u5206\u522b\u4e3a85.2%\u300173.7%\u548c68.6%\u3002\u4e5f\u5c31\u662f\u8bf4\uff0c\u5728\u7ea624\u4e2a\u6708\u65f6\uff0c\u8054\u5408\u6cbb\u7597\u7ec4\u7ea680.7%\u7684\u60a3\u8005\u4ecd\u5904\u4e8e\u65e0\u75c5\u751f\u5b58\u72b6\u6001\uff0c\u800c\u5bf9\u7167\u7ec4\u7ea6\u4e3a73.7%\u3002<\/p>\n\n\n\n

\u603b\u751f\u5b58\u7387\u65b9\u9762\uff0c\u8054\u5408\u6cbb\u7597\u7ec412\u4e2a\u6708\u300124\u4e2a\u6708\u548c30\u4e2a\u6708\u7684\u603b\u751f\u5b58\u7387\u5206\u522b\u4e3a98.3%\u300196.2%\u548c95.6%\uff1b\u5bf9\u7167\u7ec4\u5206\u522b\u4e3a98.6%\u300195.7%\u548c93.8%\u3002<\/p>\n\n\n\n

\u4ece\u76ee\u524d\u6570\u636e\u770b\uff0c\u8054\u5408\u6cbb\u7597\u5728\u65e0\u75c5\u751f\u5b58\u65b9\u9762\u663e\u793a\u51fa\u4f18\u52bf\uff0c\u4f46\u603b\u751f\u5b58\u6570\u636e\u4ecd\u9700\u66f4\u957f\u65f6\u95f4\u968f\u8bbf\u786e\u8ba4\u3002<\/p>\n\n\n\n

5. <\/strong>Belzutifan\u4e3a\u4f55\u91cd\u8981\uff1f<\/strong><\/p>\n\n\n\n

Belzutifan\u662f\u4e00\u79cdHIF-2\u03b1\u6291\u5236\u5242\uff0c\u5c5e\u4e8e\u53e3\u670d\u5c0f\u5206\u5b50\u9776\u5411\u836f\u3002<\/p>\n\n\n\n

HIF-2\u03b1\u5373\u7f3a\u6c27\u8bf1\u5bfc\u56e0\u5b50-2\u03b1\u3002\u5728\u900f\u660e\u7ec6\u80de\u80be\u7ec6\u80de\u764c\u4e2d\uff0cHIF-2\u03b1\u76f8\u5173\u901a\u8def\u5e38\u5904\u4e8e\u5f02\u5e38\u6d3b\u8dc3\u72b6\u6001\uff0c\u53ef\u53c2\u4e0e\u9a71\u52a8\u80bf\u7624\u7ec6\u80de\u751f\u957f\u548c\u75be\u75c5\u8fdb\u5c55\u3002Belzutifan\u901a\u8fc7\u6291\u5236HIF-2\u03b1\u53d1\u6325\u4f5c\u7528\uff0c\u662f\u8fd1\u5e74\u6765\u80be\u764c\u6cbb\u7597\u9886\u57df\u5177\u6709\u4ee3\u8868\u6027\u7684\u9776\u5411\u6cbb\u7597\u8fdb\u5c55\u4e4b\u4e00\u3002<\/p>\n\n\n\n

Pembrolizumab\u5219\u662f\u4e00\u79cdPD-1\u6291\u5236\u5242\uff0c\u5c5e\u4e8e\u514d\u75ab\u68c0\u67e5\u70b9\u6291\u5236\u5242\u3002\u5176\u4f5c\u7528\u673a\u5236\u662f\u5e2e\u52a9\u514d\u75ab\u7cfb\u7edf\u91cd\u65b0\u8bc6\u522b\u5e76\u653b\u51fb\u80bf\u7624\u7ec6\u80de\u3002<\/p>\n\n\n\n

\u4ece\u6cbb\u7597\u903b\u8f91\u4e0a\u770b\uff0c\u672c\u6b21\u83b7\u6279\u65b9\u6848\u5c06\u514d\u75ab\u6cbb\u7597\u4e0eHIF-2\u03b1\u9776\u5411\u6cbb\u7597\u7ed3\u5408\uff0c\u7528\u4e8e\u672f\u540e\u590d\u53d1\u98ce\u9669\u8f83\u9ad8\u7684\u900f\u660e\u7ec6\u80de\u80be\u7ec6\u80de\u764c\u60a3\u8005\u3002\u8fd9\u4e5f\u662fBelzutifan\u9996\u6b21\u83b7\u6279\u7528\u4e8e\u8f83\u65e9\u671f\u900f\u660e\u7ec6\u80de\u80be\u7ec6\u80de\u764c\u6cbb\u7597\u573a\u666f\uff0c\u540c\u65f6\u4e5f\u662fPD-1\u6291\u5236\u5242\u8054\u5408HIF-2\u03b1\u6291\u5236\u5242\u65b9\u6848\u5728\u8be5\u8f85\u52a9\u6cbb\u7597\u9886\u57df\u7684\u91cd\u8981\u83b7\u6279\u3002<\/p>\n\n\n\n

6. <\/strong>\u5b89\u5168\u6027<\/strong><\/p>\n\n\n\n

\u6574\u4f53\u6765\u770b\uff0cBelzutifan\u8054\u5408Pembrolizumab\u7ec4\u7684\u4e0d\u826f\u53cd\u5e94\u53d1\u751f\u7387\u9ad8\u4e8ePembrolizumab\u8054\u5408\u5b89\u6170\u5242\u7ec4\uff0c\u4f46\u5b89\u5168\u6027\u4e0e\u65e2\u5f80\u5df2\u77e5\u6570\u636e\u603b\u4f53\u4e00\u81f4\uff0c\u672a\u53d1\u73b0\u65b0\u7684\u5b89\u5168\u98ce\u9669\u3002<\/p>\n\n\n\n

\u5728\u7814\u7a76\u4e2d\uff0c\u8054\u5408\u6cbb\u7597\u7ec4\u6cbb\u7597\u671f\u95f4\u4e0d\u826f\u4e8b\u4ef6\u53d1\u751f\u7387\u4e3a98.9%\uff0c\u5bf9\u7167\u7ec4\u4e3a94.5%\u30023\u7ea7\u53ca\u4ee5\u4e0a\u6cbb\u7597\u671f\u95f4\u4e0d\u826f\u4e8b\u4ef6\u5728\u8054\u5408\u6cbb\u7597\u7ec4\u4e3a52.1%\uff0c\u5bf9\u7167\u7ec4\u4e3a30.2%\u3002\u4e25\u91cd\u6cbb\u7597\u671f\u95f4\u4e0d\u826f\u4e8b\u4ef6\u5728\u8054\u5408\u6cbb\u7597\u7ec4\u4e3a29.5%\uff0c\u5bf9\u7167\u7ec4\u4e3a19.9%\u3002<\/p>\n\n\n\n

\u6cbb\u7597\u76f8\u5173\u4e0d\u826f\u4e8b\u4ef6\u65b9\u9762\uff0c\u8054\u5408\u6cbb\u7597\u7ec4\u53d1\u751f\u7387\u4e3a96.6%\uff0c\u5bf9\u7167\u7ec4\u4e3a80.7%\u30023\u7ea7\u53ca\u4ee5\u4e0a\u6cbb\u7597\u76f8\u5173\u4e0d\u826f\u4e8b\u4ef6\u5728\u8054\u5408\u6cbb\u7597\u7ec4\u4e3a42.2%\uff0c\u5bf9\u7167\u7ec4\u4e3a17.9%\u3002<\/p>\n\n\n\n

\u5e38\u89c1\u4e0d\u826f\u53cd\u5e94\u5305\u62ec\u8d2b\u8840\u3001\u75b2\u52b3\u3001\u4e19\u6c28\u9178\u6c28\u57fa\u8f6c\u79fb\u9176\u5347\u9ad8\u3001\u5929\u51ac\u6c28\u9178\u6c28\u57fa\u8f6c\u79fb\u9176\u5347\u9ad8\u3001\u8179\u6cfb\u3001\u7619\u75d2\u3001\u5934\u6655\u3001\u5934\u75db\u3001\u6076\u5fc3\u3001\u5173\u8282\u75db\u3001\u7532\u72b6\u817a\u529f\u80fd\u51cf\u9000\u3001\u4e4f\u529b\u3001\u76ae\u75b9\u3001\u8840\u808c\u9150\u5347\u9ad8\u3001\u547c\u5438\u56f0\u96be\u3001\u7532\u72b6\u817a\u529f\u80fd\u4ea2\u8fdb\u548c\u54b3\u55fd\u7b49\u3002\u5176\u4e2d\uff0c\u8d2b\u8840\u662fBelzutifan\u76f8\u5173\u6cbb\u7597\u4e2d\u8f83\u4e3a\u7a81\u51fa\u7684\u4e0d\u826f\u53cd\u5e94\u4e4b\u4e00\u3002<\/p>\n\n\n\n

\u7ed3\u8bed<\/strong><\/strong><\/p>\n\n\n\n

\u603b\u4f53\u6765\u770b\uff0cBelzutifan\u8054\u5408Pembrolizumab\u4e3a\u672f\u540e\u590d\u53d1\u98ce\u9669\u8f83\u9ad8\u7684\u900f\u660e\u7ec6\u80de\u80be\u7ec6\u80de\u764c\u60a3\u8005\u5e26\u6765\u4e86\u65b0\u7684\u6cbb\u7597\u9009\u62e9\uff0c\u4e5f\u8fdb\u4e00\u6b65\u63a8\u52a8\u4e86HIF-2\u03b1\u6291\u5236\u5242\u5728\u80be\u764c\u5168\u75c5\u7a0b\u7ba1\u7406\u4e2d\u7684\u5e94\u7528\u3002<\/p>\n\n\n\n

\u8f6c\u8f7d\u8bf7\u8054\u7cfb\u6388\u6743\uff0c\u6216\u6ce8\u660e\u6765\u6e90<\/p>\n","protected":false},"excerpt":{"rendered":"

2026\u5e746\u670812\u65e5\uff0c\u7f8e\u56fd\u98df\u54c1\u836f\u54c1\u76d1\u7763\u7ba1\u7406\u5c40\uff08FDA\uff09\u6279\u51c6Belzutifan\u8054\u5408Pembrolizumab\uff0c<\/p>\n","protected":false},"author":14,"featured_media":40339,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[1769,6639],"tags":[],"yst_prominent_words":[],"class_list":["post-40349","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-treatment-zh-hans","category-6639"],"_links":{"self":[{"href":"https:\/\/www.hkioc.com.hk\/zh-hans\/wp-json\/wp\/v2\/posts\/40349","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/www.hkioc.com.hk\/zh-hans\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/www.hkioc.com.hk\/zh-hans\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/www.hkioc.com.hk\/zh-hans\/wp-json\/wp\/v2\/users\/14"}],"replies":[{"embeddable":true,"href":"https:\/\/www.hkioc.com.hk\/zh-hans\/wp-json\/wp\/v2\/comments?post=40349"}],"version-history":[{"count":1,"href":"https:\/\/www.hkioc.com.hk\/zh-hans\/wp-json\/wp\/v2\/posts\/40349\/revisions"}],"predecessor-version":[{"id":40350,"href":"https:\/\/www.hkioc.com.hk\/zh-hans\/wp-json\/wp\/v2\/posts\/40349\/revisions\/40350"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/www.hkioc.com.hk\/zh-hans\/wp-json\/wp\/v2\/media\/40339"}],"wp:attachment":[{"href":"https:\/\/www.hkioc.com.hk\/zh-hans\/wp-json\/wp\/v2\/media?parent=40349"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/www.hkioc.com.hk\/zh-hans\/wp-json\/wp\/v2\/categories?post=40349"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/www.hkioc.com.hk\/zh-hans\/wp-json\/wp\/v2\/tags?post=40349"},{"taxonomy":"yst_prominent_words","embeddable":true,"href":"https:\/\/www.hkioc.com.hk\/zh-hans\/wp-json\/wp\/v2\/yst_prominent_words?post=40349"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}