{"id":41351,"date":"2026-08-12T19:11:25","date_gmt":"2026-08-12T11:11:25","guid":{"rendered":"https:\/\/www.hkioc.com.hk\/?p=41351"},"modified":"2026-08-12T19:11:49","modified_gmt":"2026-08-12T11:11:49","slug":"psma%e9%98%b3%e6%80%a7%e8%bd%ac%e7%a7%bb%e6%80%a7%e6%bf%80%e7%b4%a0%e6%95%8f%e6%84%9f%e6%80%a7%e5%89%8d%e5%88%97%e8%85%ba%e7%99%8c%ef%bc%8c%e8%bf%8e%e6%9d%a5%e5%85%a8%e6%96%b0%e6%94%be%e5%b0%84","status":"publish","type":"post","link":"https:\/\/www.hkioc.com.hk\/zh-hans\/psma%e9%98%b3%e6%80%a7%e8%bd%ac%e7%a7%bb%e6%80%a7%e6%bf%80%e7%b4%a0%e6%95%8f%e6%84%9f%e6%80%a7%e5%89%8d%e5%88%97%e8%85%ba%e7%99%8c%ef%bc%8c%e8%bf%8e%e6%9d%a5%e5%85%a8%e6%96%b0%e6%94%be%e5%b0%84\/","title":{"rendered":"PSMA\u9633\u6027\u8f6c\u79fb\u6027\u6fc0\u7d20\u654f\u611f\u6027\u524d\u5217\u817a\u764c\uff0c\u8fce\u6765\u5168\u65b0\u653e\u5c04\u6027\u9776\u5411\u8054\u5408\u65b9\u6848"},"content":{"rendered":"\n<p>2026\u5e747\u670831\u65e5\uff0c\u7f8e\u56fd\u98df\u54c1\u836f\u54c1\u76d1\u7763\u7ba1\u7406\u5c40\uff08FDA\uff09\u6279\u51c6PSMA\u9776\u5411\u653e\u5c04\u914d\u4f53\u6cbb\u7597\u836f\u7269lutetium Lu 177 vipivotide tetraxetan\u8054\u5408\u96c4\u6fc0\u7d20\u53d7\u4f53\u901a\u8def\u6291\u5236\u5242\uff08ARPI\uff09\u7597\u6cd5\uff0c\u7528\u4e8e\u6cbb\u7597\u524d\u5217\u817a\u7279\u5f02\u6027\u819c\u6297\u539f\uff08PSMA\uff09\u9633\u6027\u7684\u8f6c\u79fb\u6027\u6fc0\u7d20\u654f\u611f\u6027\u524d\u5217\u817a\u764c\u6210\u4eba\u60a3\u8005\u3002<\/p>\n\n\n\n<p>\u672c\u6b21\u5ba1\u6279\u4f9d\u6258Orbis\u8de8\u56fd\u80bf\u7624\u540c\u6b65\u5ba1\u8bc4\u9879\u76ee\u4ee5\u53ca\u8bc4\u4f30\u8f85\u52a9\u6587\u4ef6\u673a\u5236\u5f00\u5c55\uff0c\u6574\u4f53\u5ba1\u6279\u8fdb\u5ea6\u65e9\u4e8e\u9884\u8bbe\u7684\u76ee\u6807\u671f\u9650\u3002<\/p>\n\n\n\n<figure class=\"wp-block-image size-full\"><img decoding=\"async\" width=\"692\" height=\"456\" src=\"data:image\/gif;base64,R0lGODlhAQABAIAAAAAAAP\/\/\/yH5BAEAAAAALAAAAAABAAEAAAIBRAA7\" data-src=\"https:\/\/www.hkioc.com.hk\/wp-content\/uploads\/2026\/08\/image-3-2.jpg\" alt=\"\" class=\"wp-image-41397 lazyload\" data-srcset=\"https:\/\/www.hkioc.com.hk\/wp-content\/uploads\/2026\/08\/image-3-2.jpg 692w, https:\/\/www.hkioc.com.hk\/wp-content\/uploads\/2026\/08\/image-3-2-300x198.jpg 300w\" sizes=\"(max-width: 692px) 100vw, 692px\" \/><noscript><img decoding=\"async\" width=\"692\" height=\"456\" src=\"https:\/\/www.hkioc.com.hk\/wp-content\/uploads\/2026\/08\/image-3-2.jpg\" alt=\"\" class=\"wp-image-41397 lazyload\" srcset=\"https:\/\/www.hkioc.com.hk\/wp-content\/uploads\/2026\/08\/image-3-2.jpg 692w, https:\/\/www.hkioc.com.hk\/wp-content\/uploads\/2026\/08\/image-3-2-300x198.jpg 300w\" sizes=\"(max-width: 692px) 100vw, 692px\" \/><\/noscript><figcaption class=\"wp-element-caption\">\u56fe\u6e90\uff1aFDA<\/figcaption><\/figure>\n\n\n\n<p>\u9565 [177Lu] \u7279\u6614\u7ef4\u5339\u80bd\u6ce8\u5c04\u6db2\uff0c\u5df2\u83b7\u6279\u51c6\u4e2d\u56fd\u5185\u5730\u4e0a\u5e02\uff0c\u800c\u672c\u6b21\u83b7\u6279\u7684\u9565\uff08177\uff09\u7279\u6614\u7ef4\u5339\u80bd\u6ce8\u5c04\u6db2\u8054\u5408\u96c4\u6fc0\u7d20\u53d7\u4f53\u901a\u8def\u6291\u5236\u5242\uff08ARPI\uff09\u7597\u6cd5\u5728\u5185\u5730\u5c1a\u4e0d\u53ef\u7528\uff0c\u5982\u6709\u60a3\u8005\u6b32\u8fdb\u4e00\u6b65\u4e86\u89e3\u8be6\u60c5\uff0c\u6b22\u8fce\u901a\u8fc7 <a class=\"whatsapp-link\" href=\"https:\/\/wa.me\/85268591419\" target=\"_blank\" rel=\"noopener noreferrer\"><i class=\"fab fa-whatsapp\"><\/i> <b>WhatsApp\u8054\u7edc\u6211\u4eec<\/b><\/a><\/p>\n\n\n\n<p><strong>\u4e00\u3001\u836f\u7269\u57fa\u7840\u6982\u51b5<\/strong><strong><\/strong><\/p>\n\n\n\n<p><strong>1. \u901a\u7528\u540d\u79f0\uff1a<\/strong>Lutetium Lu 177 vipivotide tetraxetan<\/p>\n\n\n\n<p><strong>2. \u6cbb\u7597\u7c7b\u522b\uff1a<\/strong>PSMA \u9776\u5411\u578b\u653e\u5c04\u914d\u4f53\u7597\u6cd5<\/p>\n\n\n\n<p>\u836f\u7269\u4f5c\u7528\u539f\u7406\u4e3a\u9776\u5411\u7ed1\u5b9a\u524d\u5217\u817a\u764c\u7ec6\u80de\u8868\u9762\u9ad8\u8868\u8fbe\u7684 PSMA \u86cb\u767d\uff0c\u4f9d\u9760\u642d\u8f7d\u7684\u653e\u5c04\u6027\u6838\u7d20\uff0c\u5b9a\u5411\u91ca\u653e\u8f90\u5c04\u635f\u4f24\u80bf\u7624DNA\uff0c\u4ee5\u6b64\u5b8c\u6210\u5b9a\u5411\u6740\u4f24\u3002<\/p>\n\n\n\n<p>\u8be5\u6b3e\u836f\u7269\u65e9\u524d\u5df2\u7ecf\u83b7\u6279\u7528\u4e8e\u540e\u7ebf\u8f6c\u79fb\u6027\u53bb\u52bf\u62b5\u6297\u6027\u524d\u5217\u817a\u764c\uff0c\u672c\u6b21\u5ba1\u6279\u5c06\u9002\u7528\u8303\u56f4\u62d3\u5c55\u81f3\u75c5\u7a0b\u66f4\u65e9\u7684\u6fc0\u7d20\u654f\u611f\u9636\u6bb5\u3002<\/p>\n\n\n\n<p><strong>\u4e8c\u3001\u83b7\u6279\u9002\u7528\u6761\u4ef6<\/strong><\/p>\n\n\n\n<p>1. \u6cbb\u7597\u5bf9\u8c61\u4e3a\u6210\u5e74\u3001PSMA \u663e\u50cf\u5448\u9633\u6027\u7684\u8f6c\u79fb\u6027\u96c4\u6fc0\u7d20\u901a\u8def\u654f\u611f\u578b\u524d\u5217\u817a\u764c\u3002<\/p>\n\n\n\n<p>2. \u6cbb\u7597\u6a21\u5f0f\u4e3a\u8be5\u653e\u5c04\u6027\u836f\u7269\u642d\u914d\u96c4\u6fc0\u7d20\u53d7\u4f53\u901a\u8def\u6291\u5236\u5242\uff08ARPI\uff09\u5f00\u5c55\u8054\u5408\u5e72\u9884\u3002<\/p>\n\n\n\n<p>3. \u60a3\u8005\u9700\u8981\u7ecf\u7531 FDA \u83b7\u6279\u7684 PSMA\u2011PET \u663e\u50cf\u5236\u5242\u68c0\u6d4b\uff0c\u8bc1\u5b9e\u75c5\u7076\u5b58\u5728 PSMA \u8868\u8fbe\u4e4b\u540e\uff0c\u65b9\u53ef\u542f\u7528\u8be5\u5957\u6cbb\u7597\u65b9\u6848\u3002<\/p>\n\n\n\n<p>4. \u4e34\u5e8a\u53ef\u4f9b\u9009\u62e9\u7684\u96c4\u6fc0\u7d20\u53d7\u4f53\u901a\u8def\u6291\u5236\u5242\uff08ARPI\uff09\u5305\u542b\u591a\u6b3e\u5df2\u7ecf\u4e0a\u5e02\u7684\u5e38\u89c4\u7528\u836f\u3002\u540c\u65f6\u60a3\u8005\u9700\u8981\u540c\u6b65\u63a5\u53d7\u836f\u7269\u53bb\u52bf\u6216\u8005\u624b\u672f\u53bb\u52bf\u5904\u7406\u3002<\/p>\n\n\n\n<p><strong>\u4e09\u3001\u652f\u6491\u5ba1\u6279\uff1aIII \u671f\u968f\u673a\u5bf9\u7167\u7814\u7a76 PSMAddition\uff08NCT04720157\uff09<\/strong><strong><\/strong><\/p>\n\n\n\n<p><strong>\u8bd5\u9a8c\u67b6\u6784<\/strong><strong><\/strong><\/p>\n\n\n\n<p>\u8be5\u591a\u4e2d\u5fc3\u5f00\u653e\u6807\u7b7e\u4e34\u5e8a\u8bd5\u9a8c\u4e00\u5171\u7eb3\u51651144\u540d\u7b26\u5408\u6807\u51c6\u7684\u53d7\u8bd5\u4eba\u5458\uff0c\u53d7\u8bd5\u8005\u6309\u71671:1\u6bd4\u4f8b\u8fdb\u884c\u5206\u7ec4<\/p>\n\n\n\n<p><strong>\u2022 \u8054\u5408\u5e72\u9884\u7ec4\uff1a<\/strong>Lutetium Lu 177 vipivotide tetraxetan+\u96c4\u6fc0\u7d20\u53d7\u4f53\u901a\u8def\u6291\u5236\u5242\uff08ARPI\uff09+\u6807\u51c6\u53bb\u52bf\u6cbb\u7597<\/p>\n\n\n\n<p><strong>\u2022 \u5bf9\u7167\u7ec4\uff1a<\/strong>\u5355\u72ec\u4f7f\u7528\u96c4\u6fc0\u7d20\u53d7\u4f53\u901a\u8def\u6291\u5236\u5242\uff08ARPI\uff09+\u6807\u51c6\u53bb\u52bf\u6cbb\u7597<\/p>\n\n\n\n<p>\u96c4\u6fc0\u7d20\u53d7\u4f53\u6291\u5236\u5242\u53ef\u6301\u7eed\u7ed9\u836f\uff0c\u76f4\u81f3\u80bf\u7624\u8fdb\u5c55\u6216\u662f\u4e0d\u8010\u53d7\u4e0d\u826f\u53cd\u5e94\u3002<\/p>\n\n\n\n<p><strong>\u4e34\u5e8a\u8bd5\u9a8c\u5173\u952e\u7ed3\u679c<\/strong><strong><\/strong><\/p>\n\n\n\n<p><strong>1. \u4e3b\u8981\u7814\u7a76\u7ec8\u70b9\u4e3a\u5f71\u50cf\u5b66\u65e0\u8fdb\u5c55\u751f\u5b58\u671f<\/strong><strong><\/strong><\/p>\n\n\n\n<p>\u76f8\u8f83\u4e8e\u5355\u836f\u6fc0\u7d20\u9776\u5411\u6cbb\u7597\u7ec4\u522b\uff0c\u8054\u5408\u65b9\u6848\u80fd\u591f\u5c06\u75be\u75c5\u8fdb\u5c55\u6216\u662f\u6b7b\u4ea1\u98ce\u9669\u4e0b\u964d28%\uff0c\u98ce\u9669\u6bd4\u503cHR=0.72\uff0895% CI\uff1a0.58\u20110.90\uff0cP=0.002\uff09\uff0c\u7edf\u8ba1\u5b66\u5dee\u5f02\u6210\u7acb\uff1b\u521d\u6b21\u968f\u8bbf\u65f6\u4e24\u7ec4\u4e2d\u4f4d\u5f71\u50cf\u5b66\u65e0\u8fdb\u5c55\u751f\u5b58\u671f\u5747\u5c1a\u672a\u62b5\u8fbe\u3002\u540e\u7eed\u66f4\u65b0\u968f\u8bbf\u6570\u636e\u663e\u793a\u98ce\u9669\u4e0b\u964d\u5e45\u5ea6\u53ef\u8fbe33%\u3002<\/p>\n\n\n\n<p><strong>2. \u6b21\u8981\u7ec8\u70b9\u603b\u751f\u5b58\u671f<\/strong><strong><\/strong><\/p>\n\n\n\n<p>\u73b0\u9636\u6bb5\u968f\u8bbf\u6570\u636e\u5c1a\u4e14\u4e0d\u6210\u719f\uff0c\u4e0d\u8fc7\u6570\u636e\u8d8b\u52bf\u504f\u5411\u8054\u5408\u6cbb\u7597\u7ec4\u522b\u5177\u5907\u751f\u5b58\u83b7\u76ca\uff0c\u98ce\u9669\u6bd4\u503cHR=0.80\uff0c\u540e\u7eed\u4f1a\u6301\u7eed\u8ddf\u8fdb\u957f\u671f\u751f\u5b58\u6570\u636e\u3002<\/p>\n\n\n\n<p><strong>\u56db\u3001\u4e34\u5e8a\u7ed9\u836f\u89c4\u8303<\/strong><strong><\/strong><\/p>\n\n\n\n<p>1. \u5355\u6b21\u8f93\u6ce8\u5242\u91cf\u8bbe\u5b9a\u4e3a 7.4 GBq\uff08200 mCi\uff09<\/p>\n\n\n\n<p>2. \u7ed9\u836f\u5468\u671f\uff1a\u6bcf\u95f4\u96946\u5468\u8fdb\u884c\u4e00\u6b21\u9759\u8109\u8f93\u6ce8\uff0c\u6700\u591a\u6267\u884c6\u4e2a\u6cbb\u7597\u5468\u671f<\/p>\n\n\n\n<p>3. \u7ec8\u6b62\u6cbb\u7597\u6761\u4ef6\uff1a\u5b8c\u6210\u5168\u90e8\u5468\u671f\u3001\u5f71\u50cf\u5b66\u63d0\u793a\u80bf\u7624\u8fdb\u5c55\u3001\u51fa\u73b0\u96be\u4ee5\u8010\u53d7\u7684\u6cbb\u7597\u6bd2\u6027\uff1b\u96c4\u6fc0\u7d20\u53d7\u4f53\u901a\u8def\u6291\u5236\u5242\uff08ARPI\uff09\u53ef\u4ee5\u7ee7\u7eed\u7ef4\u6301\u6cbb\u7597<\/p>\n\n\n\n<p><strong>\u4e94\u3001\u7528\u836f\u5b89\u5168\u6ce8\u610f\u4e8b\u9879<\/strong><strong><\/strong><\/p>\n\n\n\n<p>\u8be5\u653e\u5c04\u6027\u9776\u5411\u836f\u7269\u5b58\u5728\u591a\u9879\u9700\u8981\u5e38\u6001\u5316\u76d1\u6d4b\u7684\u6cbb\u7597\u98ce\u9669\uff0c\u4e34\u5e8a\u9636\u6bb5\u9700\u8981\u91cd\u70b9\u5173\u6ce8\u4ee5\u4e0b\u4e8b\u9879<\/p>\n\n\n\n<p>1. \u653e\u5c04\u6027\u66b4\u9732\u98ce\u9669\uff0c\u836f\u7269\u5c5e\u4e8e\u653e\u5c04\u6027\u5236\u5242\uff0c\u8f93\u6ce8\u64cd\u4f5c\u4ee5\u53ca\u60a3\u8005\u672f\u540e\u5747\u9700\u8981\u843d\u5b9e\u8f90\u5c04\u9632\u62a4\uff1b<\/p>\n\n\n\n<p>2. \u9aa8\u9ad3\u6291\u5236\u635f\u4f24\uff0c\u5b9a\u671f\u76d1\u6d4b\u8840\u5c0f\u677f\u3001\u4e2d\u6027\u7c92\u7ec6\u80de\u3001\u8840\u7ea2\u86cb\u767d\u6307\u6807\uff1b<\/p>\n\n\n\n<p>3. \u80be\u810f\u635f\u4f24\uff0c\u836f\u7269\u7ecf\u7531\u80be\u810f\u4ee3\u8c22\u6392\u6cc4\uff0c\u5168\u7a0b\u590d\u67e5\u80be\u529f\u80fd\u4ee5\u53ca\u5c3f\u86cb\u767d\u6307\u6807\uff1b<\/p>\n\n\n\n<p>4. 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